EP2025 - Early and long-term outcomes of surgical treatment in patients with slow-transit constipation

Purpose/Background: Slow-transit constipation is a form of chronic constipation characterized by prolonged colonic transit time and resistance to long-term conservative therapy. Despite a wide range of surgical treatment options, the indications for surgical intervention and the choice of optimal extent of colonic resection in such patients remain a subject of ongoing debate. This study evaluates the effectiveness of subtotal colectomy in the management of slow-transit constipation, examines potential complications, and explores the prospects for its application in clinical practice.

Aim of this study is to evaluate the effectiveness of surgical treatment for slow-transit constipation using subtotal colectomy.

Methods/Interventions: A retrospective analysis was conducted on 11 patients who underwent surgical treatment involving subtotal colectomy for slow-transit constipation between 2022 and 2024. Patient quality of life was assessed using the international Gastrointestinal Quality of Life Index (GIQLI) questionnaire before surgery, as well as 2 weeks and 2 months postoperatively.

Results/Outcomes: The analysis of the obtained data demonstrated a significant improvement in patients' quality of life across all GIQLI questionnaire parameters at both 2 weeks and 2 months following subtotal colectomy (p < 0.05). The mean total quality of life index increased by 25.4% at 2 weeks and by 28.4% at 2 months compared to preoperative values. All patients reported either complete resolution or significant reduction of pain, as well as an overall improvement in well-being. Among them, 4 patients (36.4%) rated their quality of life as "excellent," while 7 (63.6%) described it as "good."

Conclusion/Discussion: The results of the study demonstrated a significant improvement in quality of life among patients with slow-transit constipation following subtotal colectomy.

Dynamics of quality of life parameters before and at different postoperative time points (as a percentage of the maximum value for each indicator on the GIQLI scale in the Sandblom modification).