EP892 - Impact of Surgery on Beck Depression Inventory Scores in Patients with Inflammatory Bowel Disease: A ProspectiveCohort Study

Monday, May 11, 2026

1:36 PM - 1:41 PM ET

ePoster Presenter(s)

Mohammed Alharthi, MD, DES, DESC

associate professor, consultant general surgery and colorectal surgery and HBP surgery
associate professor, deparrtment of surgery, faculty of medicine, king abdulaziz university, jeddah, Saudi arabia
King Abdulaziz University
Jeddah, Makkah, Saudi Arabia

All disclosed relationships have been reviewed and managed prior to the start of this activity. Any relevant relationships will be listed below. This individual has no financial relationships to disclose

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Author(s)

Mg

Mohammed ghunaim, n/a

assistant professor
assistant professor, department od surgery, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
aS

adbulaziz Saleem, n/a

associate professor,
associate professor, department of surgery, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
HA

Hassan Alturki, n/a

assistant professor
assistant professor, department of surgery, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
MB

Mohammed Basendowah, n/a

associate professor
associate professor, department of surgery, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
Jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
NM

Nadim Malibary, n/a

associate professor
associate professor, department of surgery, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
AF

Ali Farsi, n/a

associate professor
associate professor, department of surgery, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
Jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
SS

Samara Suliman, n/a

assistant professor
assistant professor, department of Medicine, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
Jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
HA

Hussain Alkhalifa, n/a

General surgery resident
department of surgery, king abdulaziz university hospital, jeddah, saudi arabia
Jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
MM

Mohmoud Mosli, n/a

professor
professor, department of Medicine, faculty of medicine, king abdulaziz university, jeddah, saudi arabia
Jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
sA

shahad Almughamsi, n/a

General surgery resident
department of surgery, king abdulaziz university hospital, jeddah, saudi arabia
Jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.
NA

Nouf Akeel, M.D

Associate professor of surgery
King Abdulaziz University
Jeddah, Makkah, Saudi Arabia

Disclosure information not submitted.

Purpose/Background: Depression is a common comorbidity in inflammatory bowel disease (IBD), affecting nearly 20% of the IBD pateints. The chronic and relapsing nature of IBD detrimentally impacts quality of life, with bidirectional brain-gut interactions contributing to psychological distress. Although surgery is often necessary for disease control, its effect on mental health remains poorly studied. This study aimed to evaluate changes in depressive symptoms following surgical resection in IBD patients and explore the association of postoperative depressive symptoms with the inflammatory and nutritional markers.

Methods:
This prospective cohort study included patients aged >15 years with IBD who underwent elective or emergency surgical resection between 2023 and 2025. Patients younger than 15 years and those lost to 30-day follow-up were excluded. Depressive symptoms were assessed using a validated Arabic version of the Beck Depression Inventory-I (BDI-I) preoperatively and one month after the final surgery. For patients who underwent stoma formation, reassessment occurred one month after stoma reversal. A BDI-I score ≥16 prompted referral to psychiatric services. The primary outcome was the psychiatric status one month after the final procedure, while the secondary outcome compared depressive symptoms between patients with and without stoma. Postoperative albumin and C-reactive protein were analyzed for correlation with depressive symptoms.

Results:
A total of 37 patients with IBD were included; The majority had Crohn’s disease (n= 34, 91.9%) and the rest had ulcerative colitis (n=3, 8.1%). Surgery significantly decreased depressive symptoms, measured by the BDI-I score (preoperative median: 7.00, IQR: 3.00 – 16.50; one month postoperative median: 1.00, IQR: 0.00 – 3.00; p <0.001). Of the total, 20 patients (54.1%) required a stoma at the first surgery. BDI-I score also decreased from a median of 1.00 (IQR: 0.00 – 3.00) onemonth after surgery to 0.00 (IQR: 0.00 – 0.00) after stoma reversal, though the change was not statistically significance. Additionally, lower postoperative albumin levels were significantly correlated with higher BDI-I scores one month after surgery (r -0.361, p= 0.028).

Conclusion:
Depression is highly prevalent in IBD patients requiring surgery. Surgical resection significantly improves depressive symptoms, highlighting the need for routine psychological screening in perioperative care. This is especially important for patients with poor postoperative nutritional status, to ensure early identification and timely mental health referral.