RF103 - Psychiatric Disorders May Be Associated With Longer Hospital Stay After Colon Resection in an Exploratory Analysis of a Multinational Cohort

Abstract Podium Presenter(s)

• KN

  Katerina Neumann, MSc Md/PhD

  Colorectal Surgeon
  Dalhousie University
  Halifax, Nova Scotia, Canada

  All disclosed relationships have been reviewed and managed prior to the start of this activity. Any relevant relationships will be listed below. This individual has no financial relationships to disclose

Author(s)

• AO

  Adele Orovec, MD

  General Surgery Resident
  Dalhousie University
  Halifax, Nova Scotia, Canada

  Disclosure information not submitted.
• LA

  Latefa Y A Y A AlMazroui, MD

  General Surgery resident
  Dalhousie university
  Halifax, Nova Scotia, Canada

  All disclosed relationships have been reviewed and managed prior to the start of this activity. Any relevant relationships will be listed below. This individual has no financial relationships to disclose
• TL

  Tongtong Li, MSc, MB

  Research Coordinator
  Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
  Halifax, Nova Scotia, Canada

  Disclosure information not submitted.
• DY

  David Yabar, n/a

  Statistician
  Dalhousie University
  Halifax, Nova Scotia, Canada

  Disclosure information not submitted.
• RS

  Richard T. Spence, MD FRCS PhD

  Colorectal surgeon/ surgical oncologist
  Dalhousie University
  Halifax, Nova Scotia, Canada

  Disclosure information not submitted.
• BG

  Boris Gala-Lopez, MD, MSc, PhD.

  Assistant Professor
  Dalhousie University
  Halifax, Nova Scotia, Canada

  Disclosure information not submitted.
• BE

  Bassey Enodien, n/a

  Deputy Cheif of Surgery
  Kantonspital Glarus
  Glarus, Glarus, Switzerland

  Disclosure information not submitted.
• DF

  Daniel M. Frey, board cerified visceral surgeon (Switzerland)

  Head of Bariatric Surgery Cantonal Hospital of Baden
  University of Basel, Switzerland
  Baden, Aargau, Switzerland

  Disclosure information not submitted.
• SV

  Stephan A. Vorburger, n/a

  Head Dept. Surgery
  none
  Burgdorf, Bern, Switzerland

  Disclosure information not submitted.
• SF

  Sven Flemming, SF

  Vice Chair
  Department of Surgery I, University Hospital Wuerzburg
  Wuerzburg, Bayern, Germany

  Disclosure information not submitted.
• JG

  Julia-Kristin Grass, n/a

  Consultant Visceral Surgery
  General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf
  Hamburg, Hamburg, Germany

  Disclosure information not submitted.
• TP

  Tomas Poskus, n/a

  Professor
  Vilnius University
  Vilnius, Vilniaus Apskritis, Lithuania

  Disclosure information not submitted.
• FP

  Florian Ponholzer, n/a

  Surgeon, Local Project Lead
  Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck
  Innsbruck, Tirol, Austria

  Disclosure information not submitted.
• HK

  Helga Komi, Doctor

  Surgery-Resident
  Department of Visceral, Transplant and Thoracic Surgery, Center of Operative Medicine, Medical University of Innsbruck, Innsbruck, Austria
  Innsbruck, Tirol, Austria

  Disclosure information not submitted.
• OB

  Ovunc Bardakcioglu, MD, FACS, FASCRS

  Chief of Colorectal Surgery
  Kirk Kerkorian School of Medicine at UNLV
  Las Vegas, Nevada, United States

  Disclosure information not submitted.
• MH

  Michael Honaker, MD, FACS, FASCRS

  Associate Professor
  East Carolina University Brody School of Medicine
  Winterville, North Carolina, United States

  Disclosure information not submitted.
• AT

  Anas Taha, Surgery

  MD
  Kantonspital Baselland
  Basel, Basel-Landschaft, Switzerland

  Disclosure information not submitted.
• OK

  Otto Kolmar, n/a

  Senior Consultant for Visceral and Hepatopancreatobiliary Surgery
  KSBL Liestal
  Liestal, Basel-Landschaft, Switzerland

  Disclosure information not submitted.
• RR

  Robert Rosenberg, MD

  Chief of department
  Kantonsspital Baselland
  Liestal, Basel-Stadt, Switzerland

  Disclosure information not submitted.
• DS

  Daniel C. Steinemann, MD

  Deputy Chief Surgeon
  Clarunis - Universitäres Bauchzentrum Basel
  Basel, Basel-Stadt, Switzerland

  Disclosure information not submitted.
• BP

  Beat P Müller, none

  Head of Department
  University Digestive Healthcare Center Basel
  Basel, Basel-Stadt, Switzerland

  Disclosure information not submitted.
• ST

  Stephanie Taha-Mehlitz, n/a

  Consultant
  Department of Surgery, Clarunis University Digestive Health Care Center Basel, Basel, Switzerland
  Basel, Schweiz, Basel-Stadt, Switzerland

  Disclosure information not submitted.
• GK

  Gregory Knapp, FRCSC

  Assistant Professor
  Dalhousie University / Nova Scotia Health
  Halifax, Nova Scotia, Canada

  Disclosure information not submitted.
• FF

  Farsan Faghiri-Wannig, n/a

  General practitioner
  Faculty of Medicine, University Basel, Basel, Switzerland
  Basel City, Basel-Stadt, Switzerland

  Disclosure information not submitted.
• VO

  Vincent Ochs, n/a

  PhD Student
  Department of Biomedical Engineering, University Basel
  Basel, Basel-Stadt, Switzerland

  Disclosure information not submitted.

Purpose/Background: Psychiatric disorders significantly impact clinical health outcomes, including postoperative recovery, posing significant challenges to healthcare systems. Previous research has demonstrated that patients with underlying psychiatric disorders experience worse surgical outcomes, have longer lengths of stay (LOS), and higher medical costs. There is a paucity of quality evidence with larger patient cohorts that evaluate the impact of psychiatric disorders on surgical outcomes in colorectal surgery. The primary objective of this study is to evaluate the association between psychiatric disorders and LOS after colorectal surgery in a multinational cohort.

Methods/Interventions: A retrospective clinical dataset of colorectal resections from across 6 hospitals spanning Europe, Canada and the USA was utilized in this analysis. 3,414 patients who had a colon resection between January 2012 and December 2021 were included. Data abstracted included patient factors, surgical factors, and disease factors known to influence LOS. A generalized linear mixed model was used to run regressions with site as the random effect, in an exploratory manner.

Results/Outcomes: In our cohort of 3,414 patients, the mean age was 57.5 years, 48.1% female, with a median ASA score of 2.0. Underlying psychiatric disorder was found in 502 patients (14.7%), with depression being the most prevalent of the disorders (31.5%), followed by anxiety (15.5%). The median LOS for the cohort was 9.0 days [IQR 6.0-15.0]. Exploratory modeling of the association between psychiatric disorder and LOS demonstrated a signal consistent in direction and magnitude in favor of longer LOS with any psychiatric disorder, with the strongest signal demonstrated in patients suffering from depression. Underlying psychiatric disorder translated to approximately one extra day in hospital after colon resection.

Conclusion/Discussion: Our findings demonstrate an association between underlying psychiatric disorder and increased LOS in colorectal surgery patients and underscore the importance of considering mental health, particularly depression, in the management of colorectal surgery patients.

Summary of Modelling Association between Psychiatric Disorder and LOS.
Sensitivity analysis