Skip to main content
2026 ASCRS Annual Scientific Meeting Main banner
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Presentation Icons
CME
CME
Invitation/Ticketed Event
Invitation/Ticketed Event
Invited Lectureship
Invited Lectureship
Award Recipient
Award Recipient
Live Streamed Session
Live Streamed Session
Nurses Contact Hours
Nurses Contact Hours
Self-Assessment
Self-Assessment
Live Q&A and Polling
Live Q&A and Polling
Social
Social
Industry
Industry

Session:: ePosters-Sun800-M1: Rectal Cancer

EP202 - Clinical Features, Therapeutic Strategy and Prognosis in Anorectal Malignant Melanoma: A Single-Center Retrospective Study.

Sunday, May 10, 2026
8:16 AM - 8:21 AM ET

    ePoster Presenter(s)

  • Aiwen Wu, MD, PhD

    Chief, GI Cancer Center, Unit III
    Peking University Cancer Hospital
    Peking University Cancer Hospital & Institute
    Beijing, Beijing, China (People's Republic)

    All disclosed relationships have been reviewed and managed prior to the start of this activity. Any relevant relationships will be listed below. This individual has no financial relationships to disclose

    • Author(s)

  • Nan Chen

    Chief Surgeon
    Beijing Cancer Hospital
    Beijing Cancer Hospital
    Beijing, Beijing, China (People's Republic)

    Disclosure information not submitted.

    View ePoster

    • Author(s)

  • Jianning Zhai, MD/PhD

    Attending physician
    Peking University Cancer Hospital
    Peking University Cancer Hospital
    Beijing, Beijing, China (People's Republic)

    All disclosed relationships have been reviewed and managed prior to the start of this activity. Any relevant relationships will be listed below. This individual has no financial relationships to disclose

  • LW

    Lin Wang, n/a

    Fuchenglu Rd 52
    Peking University Cancer Hospital
    Beijing, Beijing, China (People's Republic)

    Disclosure information not submitted.

Purpose/Background: Anorectal malignant melanoma (ARMM) is a rare mucosal melanoma that arises in a special anatomical location, relevant studies were relatively limited. This study planned to investigate prognostic factors that influence survival of ARMM patients.

Methods/Interventions: Clinical and pathological results of 111 ARMM patients, who underwent abdominal- perineal resection (APR) and wide local excision (WLE) in Gastrointestinal Cancer Center of Peking University Cancer Hospital from 2005 to 2023, were retrospectively analyzed. Univariate and multivariate analyses of prognostic factors and overall survival (OS) were performed by using the Cox proportional hazards regression. Survival rate of these ARMM patients was calculated by Kaplan-Meier survival analysis.

Results/Outcomes: The median survival time of 111 ARMM patients was 23(2-97) months. Among the 111 patients with ARMM, 43 (38.7%) were male, 68 (61.3%) were female. The results of univariate analysis demonstrated that tumor diameters (>2 cm), tumor invasion depth (> 2mm), tumor number (n>1), lymph node metastasis and the preoperative distant metastases were the main prognostic factors. Preoperative distant metastasis was the independent factor by multivariate analysis. Additionally, both surgical methods (APR vs WLE) and immunotherapy could not affect the survival of ARMM patients by Cox regression and Kaplan-Meier survival analysis. Finally, staging classification by Jun Guo et al have the same advantages of patients with ARMM as compared to staging classification by Falch et al.

Conclusion/Discussion: This study identifies that preoperative distant metastasis was an independent predictor of poor survival in patients with ARMM. Notably, surgical approach (APR vs WLE) and adjuvant immunotherapy have no advantage on the survival of ARMM patients. Both Jun Guo and Falch staging systems effectively stratified survival outcomes in different stages of ARMM.

Figure 1 Clinicopathological factors related to the overall survival of patients with ARMM were analyzed by Kaplan-Meier survival curves